Methods and devices related to amplifying nucleic acid at a variety of temperatures
AssigneeBoard of Regents, The University of Texas System
InventorsAndrew Ellington, Cheulhee Jung, Sheng Cai, Sanchita Bhadra, John N. Milligan, Daniel Garry, Raghav Shroff
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Abstract
Disclosed are compositions and methods for nucleic acid amplification and detection. Specifically, disclosed herein are compositions and methods that allow for amplification of nucleic acids at a wide variety of temperatures. This includes a polymerase which is thermostable at high temperatures, and a method of amplification that can be conducted at relatively low temperatures.
Claims8
A non-naturally occurring thermostable polymerase, wherein the thermostable polymerase has at least 97% sequence identity to SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.