SIRP alpha-CD70 fusion protein and methods of use thereof
AssigneeKAHR Medical Ltd.
InventorsNoam Shani, Yosi Gozlan, Michal Dranitzki Elhalel, Edwin Bremer, Ido Kaminsky
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Abstract
SIRPalpha-CD70 fusion proteins are provided. Accordingly, there is provided a SIRPalpha-CD70 fusion protein comprising a single amino acid linker between the SIRPalpha and the CD70. Also there is provided a SIRPalpha-CD70 fusion protein in a form of at least a homo-trimer. Also provided are polynucleotides and nucleic acid constructs encoding the SIRPalpha-CD70 fusion protein, host-cells expressing the SIRPalpha-CD70 fusion protein and methods of use thereof.
Claims7
A SIRPα-CD70 fusion protein being characterized by a single amino acid linker between said SIRPα and said CD70;
- and in a form of at least a homo-trimer, wherein said SIRPα-CD70 fusion protein amino acid sequence comprises SEQ ID NO:
- 1.
Dependencies are inferred from the claim text.