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US 11,299,469 B2Granted
Naphthofuran derivatives, preparation, and methods of use thereof
AssigneeSumitomo Dainippon Pharma Oncology, Inc.
InventorsJeevanandam Arumugasamy, Wei Li
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Abstract
Provided herein are methods of preparation of I by reacting i with acid where R1 and R2 are each independently a leaving group. Intermediates to make i are also claimed.
Claims22
A method of making a compound having formula (I):
- or a prodrug, a pharmaceutically acceptable salt, or a solvate thereof;
- comprising reacting a compound having formula (i):
- or a salt or solvate thereof, with an acid;
- wherein R1 and R2 each independently is a leaving group.
1 more element
Dependencies are inferred from the claim text.