Back to results
US 11,299,461 B2Granted
Pyridin-2-yl alkylamino substituted hydroxamic acid and uses thereof
AssigneeHawaii Biotech, Inc.
InventorsGuan-Sheng Jiao, Seong Jin Kim, Alan T. Johnson
Life of this patent
Estimating the term…
Abstract
Compounds of formula I are provided: wherein X is NH, or CH2, Y is a single bond, or —CHR5—, R1 is H, C1-C4 alkyl, or C1-C4 hydroxyalkyl, R2 and R2′ are each independently H, C1-C4 alkyl, or C1-C4 hydroxyalkyl, each R3 is independently H, halo, —CF3, C1-C4 alkyl, or C1-C4 alkoxy, C3 perhaloalkyl, each R4 is independently H, halo, or C1-C4 alkyl, R5 is C1-C4 alkoxy, r is integer from 0 to 3; and p is integer from 0 to 3.
Claims21
A compound of formula I:
- or a pharmaceutically acceptable salt, hydrate or solvate thereof
- wherein
- X is NH or CH2;
- Y is a single bond, or —CHR5—;
- R1 is H, C1-C4 alkyl, or C1-C4 hydroxyalkyl;
- R2 and R2′ are each independently H, C1-C4 alkyl, or C1-C4 hydroxyalkyl;
- each R3 is independently H, halo, —CF3, C1-C4 alkyl, or C1-C4 alkoxy, C3 perhaloalkyl;
- each R4 is independently H, halo, or C1-C4 alkyl;
- R5 is C1-C4 alkoxy;
- r is integer from 0 to 3;
- and
- p is integer from 0 to 3.
9 more elements
A compound selected from:
- or a pharmaceutically acceptable salt, hydrate or solvate thereof.
Dependencies are inferred from the claim text.