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US 11,298,698 B2Granted
Method and system for performing heat assisted biochemical reactions
AssigneeKryptos Biotechnologies, Inc.
InventorsJun Ho Son, Sewoon Han, Jinyong Lee
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Abstract
Systems and methods for light based heating of light absorbing sources for modification of nucleic acids through fast thermal cycling of polymerase chain reaction are described.
Claims20
A system comprising:
- a transparent block comprising one or more concave intrusions;
- a light absorbing film deposited within the one or more concave intrusions of the transparent block;
- a reaction vessel removably positioned onto the concave intrusions of the transparent block;
- a sealing film disposed on the reaction vessel;
- and
- a light source;
- wherein the light source is configured to be directed at the concave intrusions of the transparent block such that light from the light source passes through the transparent block to the light absorbing film in the concave intrusions to generate heat within the light absorbing film and subsequent heating of the reaction vessel.
4 more elements
A system comprising:
- a polymeric reaction vessel comprising one or more wells;
- a light absorbing film deposited within the one or more wells of the polymeric reaction vessel;
- a transparent block with concave intrusions to hold the polymeric reaction vessel;
- a light source configured to be directed at the concave intrusions of the transparent block such that light from the light source passes through the transparent block to the light absorbing film in the concave intrusions to generate heat within the light absorbing film and heats the polymeric reaction vessel;
- and
- a sealing film disposed on the polymeric reaction vessel.
3 more elements
Dependencies are inferred from the claim text.