Intra-ventricular infusion and evacuation catheter for treatment of intracerebral hemorrhage (ICH)

A method of treating an anatomical cavity within a brain of a patient using an infusion/aspiration catheter, wherein the patient has clot residing within the anatomical cavity as a result of a hemorrhagic stroke suffered by the patient, the infusion/aspiration catheter comprising an elongate catheter body having a proximal end, a distal end, at least one infusion lumen, and an aspiration lumen extending between the proximal end and the distal end, the aspiration lumen terminating in a distal fluid port at the distal end of the elongate catheter body, a plurality of arms respectively having proximal ends affixed together at the distal end of elongate catheter body, the distal fluid port of the elongate catheter body being between the proximal ends of the plurality of arms, the arms having lumens in fluid communication with the at least one infusion lumen, each of the arms having at least one fluid port in fluid communication with the lumen of the respective arm, at least one infusion connector affixed to the proximal end of the elongate catheter body in fluid communication with the at least one infusion lumen, and an aspiration connector affixed to the proximal end of the elongate catheter body in fluid communication with the at least one aspiration lumen, the method comprising:

• introducing the infusion/aspiration catheter into the patient, such that the plurality of arms reside within the anatomical cavity;
• delivering a fluid comprising recombinant tissue plasminogen activator (rt-PA) into the at least one of the infusion connector, such that fluid exits the at least one fluid port of each of the plurality of arms, thereby infusing the anatomical cavity with the fluid and the infused rt-PA dissolves the clot;
• and
• aspirating the fluid, along with dissolved clot, into the distal fluid port of the elongate catheter body, such that the fluid, along with dissolved clot, exits the aspiration connector.