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AssigneeSami Labs Limited
InventorsMuhammed Majeed, Kalyanam Nagabhushanam, Furqan Ali, Sivakumar Arumugam, Shaheen Majeed, Lakshmi Mundkur, Anurag Pande
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The present invention discloses a composition comprising heat inactivated spores and/or comprising heat inactivated vegetative cells of probiotic bacteria Bacillus coagulans, and a process for preparing the same. The invention also discloses a method of modulating immune function in mammals by activating macrophages, using a composition comprising Bacillus coagulans in the form of live or heat inactivated spore and/or vegetative cells.
A method of modulating immune function by macrophage polarization in mammals, said method comprising step of bringing into contact mammalian macrophages with an effective concentration of Bacillus coagulans MTCC 5856 in the form of spore or vegetative cells, to bring about the effect of immune modulation by polarizing macrophages to M1 type.
Dependencies are inferred from the claim text.