Methods and products for preventing and/or treating microorganism infections comprising iron chelators and non-iron porphyrins
AssigneeThe University of Adelaide
InventorsSarah Vreugde, Peter John Wormald
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Abstract
The present disclosure relates to methods and products for reducing the viability of microorganisms, and to methods and products for preventing and/or treating microorganism infections. Certain embodiments of the present disclosure provide a method for reducing viability of a microorganism. The method comprises exposing the microorganism to an effective amount of an iron chelator and subsequently exposing the microorganism to an effective amount of a non-iron porphyrin, thereby reducing the viability of the microorganism.
Claims17
A method of preventing and/or treating a microorganism infection in a subject, the method comprising administering to the subject an effective amount of an iron chelator and subsequently administering to the subject an effective amount of a non-iron porphyrin, thereby preventing and/or treating the microorganism infection.
A hydrogel composition for the prevention and/or treatment of a bacterial infection in a subject comprising an iron chelator and a non-iron porphyrin, wherein the composition provides an immediate or sustained release of the iron chelator and a delayed release of the non-iron porphyrin.
A method for reducing viability of a microorganism, the method comprising exposing the microorganism to an effective amount of an iron chelator and subsequently exposing the microorganism to an effective amount of a non-iron porphyrin, thereby reducing the viability of the microorganism.
Dependencies are inferred from the claim text.