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US 11,298,338 B2Granted
Compositions and methods for cancer therapy
AssigneeUniversity of Iowa Research Foundation
InventorsFenghuang Zhan, Ivana Frech, Guido Tricot
Life of this patent
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Abstract
The invention provides compositions and methods to treat a hyperproliferative disorder with ascorbate or a pharmaceutically acceptable salt thereof, and one or more anti-cancer therapies.
Claims8
A method of treating a hyperproliferative disorder associated with high intracellular iron comprising administering pharmacological ascorbic acid or a pharmaceutically acceptable salt thereof and melphalan, wherein the pharmacological ascorbic acid is administered at a dose of about 15 g-100 g, wherein the hyperproliferative disorder is smoldering multiple myeloma.
Dependencies are inferred from the claim text.