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AssigneesChanel Parfums Beaute, Kyushu Univeristy, National University Corporation
InventorsMasayoshi Miyamoto, Yoshihito Oda, Masahiro Goto
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A method for producing a nonaqueous composition for external use on the skin including a strongly hydrophilic amphiphilic solid active ingredient-surfactant complex dissolved or dispersed in an oil phase, the method including the steps of: dissolving a surfactant in an oil phase to obtain a surfactant solution; mixing the obtained surfactant solution with a strongly hydrophilic amphiphilic solid active ingredient to obtain a suspension; and allowing the obtained suspension to stand still to obtain a transparent composition. Unlike conventional methods for preparing S/O formulations, the strongly hydrophilic amphiphilic solid active ingredient can be solubilized in an oil phase without the process of emulsification and freeze drying.
A method for producing a nonaqueous composition for external use on the skin comprising a strongly hydrophilic amphiphilic solid active ingredient-surfactant complex dispersed in an oil phase, the strongly hydrophilic amphiphilic solid active ingredient being selected from the group consisting of palmitoyl-L-carnitine, hydroxycitryl palmitate, ascorbyl phosphate palmitate, (ascorbyl/tocopheryl) phosphate, cyclic lysophosphatidic acid, and salts thereof, the method being operated in the absence of water, and comprising the steps of:
Dependencies are inferred from the claim text.