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US 11,298,225 B2Granted
Medical implant with seamlessly connected bacterial cellulose
AssigneeBIOTRONIK SE & Co. KG
InventorsAlexander Rzany, Tina Pieger, Bernhard Hensel
Life of this patent
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Abstract
An implant has a support structure (e.g., alloplastic) such as a stent or a scaffold, and a functional element (e.g., a heart valve) including or made of bacterial cellulose. At least a part of the support structure is embedded in the functional element or in an extension thereof so as to connect the functional element to the structural element via positive fit.
Claims9
An implant with a support structure and a functional element produced by a method comprising the following steps:
- a) providing the support structure, the support structure having a three-dimensional shape;
- b) providing a three-dimensional mold of the functional element;
- c) positioning the mold relative to the support structure;
- d) providing a medium comprising a bacterial cellulose-producing bacteria such that the medium contacts the mold and the support structure;
- e) subjecting the mold, the support structure, and the medium to bacterial cellulose-growing conditions to grow bacterial cellulose on, in, or on and in the mold (1) to form the functional element from the bacterial cellulose and (2) to embed at least a part of the support structure in at least a part of the bacterial cellulose of the functional element, thereby connecting the functional element to the support structure;
- and
- f) drying the bacterial cellulose at a temperature of from 40 to 70° C.,
- thereby forming the functional element comprised of non-swellable bacterial cellulose and having a three-dimensional shape that deviates at least in part from the three-dimensional shape of the support structure, wherein at least a part of the support structure is embedded in the functional element.
5 more elements
Dependencies are inferred from the claim text.