In-vivo pressure monitoring system

A system for in-vivo monitoring of pressure of a body fluid, the system comprising:

• a delivery component of a cannula type being configured to penetrate through an abdominal wall of the patient and further through a location on the bladder wall into the interior volume;
• a flexible elongate sensor delivery member shaped so as to pass through the delivery component when the delivery component has penetrated the bladder wall in order to allow the sensor delivery member to enter into the interior volume of the bladder;
• and
• a first pressure sensor being positioned at a distal rounded end region of the delivery member that is inserted into the bladder interior of the patient, the first pressure sensor measuring and providing a first pressure data of the body fluid in the bladder, the first pressure sensor being integrally connected to a distal tip part of a sensor delivery member during insertion through the delivery component into the patient bladder, and the sensor delivery member and the first pressure sensor having lesser diameter than the delivery component;
• a second pressure sensor configured to be inserted subcutaneously into the abdominal region of the patient, the second pressure sensor measuring and providing a second pressure data that may influence the first pressure data;
• and
• an external signal processing component located remotely from the abdominal wall surface of the patient, configured to receive and process the first pressure data and the second pressure data while the patient is engaged in ambulatory movement, calculate a differential signal between the first pressure data and the second pressure data and automatically adjust the first pressure data based on the calculated differential while the patient is engaged in ambulatory movement, thereby compensating for variations in pressure caused at least in part by the patient's ambulatory movement, and
• the adjustment of the first pressure data based on the calculated differential with the second pressure data being performed based on the readings from the first and second pressure sensors, as received and adjusted while the patient is engaged in the ambulatory movement,
• and the adjustment automatically compensating for the internal organ activity caused by the ambulatory movement of the patient.

A system for in-vivo monitoring of pressure of a body fluid in a urinary bladder of a patient, the system comprising:

• a delivery component of a cannula type configured to be penetrable through an abdominal wall of the patient and further through a wall of the bladder interior;
• a flexible elongate sensor delivery member shaped so as to pass through the delivery component when the delivery component has penetrated the bladder wall in order to allow the sensor delivery member to enter into the bladder of the patient;
• and
• a first pressure sensor positioned at a distal rounded end of the delivery member that is inserted into the bladder interior, the first pressure sensor measuring and providing a first pressure data of the body fluid inside the bladder;
• a second pressure sensor configured to be inserted subcutaneously into the abdominal region adjacent the bladder or into another organ that is different from the bladder,
• an external signal processing component located remotely from the abdominal wall of the patient, configured to receive and process the first pressure data while the patient is engaged in ambulatory movement,
• wherein the first pressure data and the second pressure data are received by the external processing component through separate electronic modules and to be calculated into a differential signal, and
• wherein the external signal processing component provides an output to a user based upon the received first pressure data and the calculated differential signal.