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US 11,298,010 B2Granted
Imaging and collection device and related systems and methods
AssigneesUniversity of Kansas, Department of Veterans Affairs
InventorsAjay Bansal, Lane Christenson, Nick Baker, Ryan Baskins, John Stark, Nourouddin Sharifi, Hadi Kh A Kh Alzuabi, Parker Gill
Life of this patent
Estimating the term…
Abstract
Disclosed herein are devices having both imaging components and cell collection apparatuses. More specifically, the various embodiments disclosed herein include swallowable capsules having deployable collection structures, expansion structures to deploy the collection structures, and imaging components.
Claims20
A swallowable capsule comprising:
- (a) a core component;
- (b) a plurality of deployment structures operably coupled to the core component, wherein the deployment structures are configured to move between an undeployed configuration and a deployed configuration;
- (c) at least one collection structure coupled to each of the plurality of deployment structures;
- (d) an expansion component disposed within the core component, wherein expansion of the expansion component urges the plurality of deployment structures toward the deployed configuration;
- (e) an outer casing comprising a plurality of openings corresponding to the plurality of deployment structures, wherein the plurality of openings are configured to receive the at least one collection structures when the deployment structures are disposed in the deployed configuration such that the at least one collection structures protrude out of the openings;
- and
- (f) an imaging component disposed on the capsule.
4 more elements
A swallowable capsule comprising:
- (a) a capsule body comprising an outer casing;
- (b) a plurality of deployment structures disposed within the body, wherein the deployment structures are configured to move between an undeployed configuration and a deployed configuration;
- (c) at least one collection structure coupled to each of the plurality of deployment structures;
- (d) a plurality of openings defined in the outer casing, wherein the plurality of openings correspond to the plurality of deployment structures, wherein the plurality of openings are configured to receive the at least one collection structures when the deployment structures are disposed in the deployed configuration such that the at least one collection structures protrude out of the openings;
- (e) an expansion component disposed within the capsule body adjacent to the plurality of deployment structures, wherein expansion of the expansion component causes the plurality of deployment structures to move toward the deployed configuration;
- and
- (f) an imaging component disposed on the capsule body.
4 more elements
A method of diagnosing a condition of the esophagus or the stomach of a patient, comprising:
- positioning a swallowable capsule in the esophagus or stomach of the patient, the swallowable capsule comprising:
- (a) a capsule body comprising an outer casing;
- (b) a plurality of deployment structures disposed within the body;
- (c) at least one collection structure coupled to each of the plurality of deployment structures;
- (d) a plurality of openings defined in the outer casing, wherein the plurality of openings correspond to the plurality of deployment structures;
- (e) an expansion component disposed within the capsule body adjacent to the plurality of deployment structures;
- and
- (f) an imaging component disposed on the capsule body
- collecting cells with the swallowable capsule by expanding the expansion component and thereby urge the plurality of deployment structures into a deployed configuration such that each of the at least one collection structure protrudes through one of the plurality of openings and contacts a target tissue;
- and
- removing the swallowable capsule from the patient.
8 more elements
Dependencies are inferred from the claim text.