Convectively controlled adiabatic column chamber for use in chromatographic systems

An enclosure, comprising:

• a column chamber having chamber walls enclosing an open chamber, the open chamber adapted to hold one or more chromatography separation columns;
• a duct system providing an airflow path around the column chamber such that the one or more chromatography separation columns held within the column chamber are isolated from the airflow path;
• an air mover disposed in the airflow path, the air mover generating a flow of air within the duct system;
• and
• a heat exchanger system disposed in the airflow path near the air mover, the heat exchanger system configured for exchanging heat with the air as the air flows past the heat exchanger system such that the air circulates through the duct system around the column chamber and convectively exchanges heat with the chamber walls such that heat radiates from the chamber walls to produce a thermally conditioned environment within the column chamber without airflow in the column chamber.