Bone implants for the treatment of infection
AssigneeSilver Bullet Therapeutics, Inc.
InventorsHoudin Dehnad, Bohdan Wolodymyr Chopko, Paul E. Chirico
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Abstract
Described herein are devices, systems and methods for treating disease and/or infection by the release of silver from an implant over an extended period of time. In particular, the devices described herein may be used to treat infections such as osteomyelitis by the controlled release of silver ions from multiple sites of an extended-use implant. This implant typically includes a plurality of arms that both anchor and help distribute the released ions within the tissue. Power may be applied to release the silver ions into the tissue.
Claims17
A bone implant to treat or prevent infection, the implant comprising:
- an implant body configured to be coupled to a bone;
- a removable antimicrobial ion releasing member comprising an antimicrobial ion reservoir configured to be coupled to the implant body;
- a galvanic reactor metal on the implant body;
- wherein the implant is configured to galvanically drive release of antimicrobial ions when the galvanic reactor metal on the implant body is in electrical communication with the antimicrobial ion reservoir.
A bone implant to treat or prevent infection, the implant comprising:
- an implant body having a threaded region configured to be coupled to a bone;
- a removable antimicrobial ion releasing member comprising an antimicrobial ion reservoir configured to be coupled to the implant body within a channel in the implant body;
- a galvanic reactor metal on the implant body;
- wherein the implant is configured to galvanically drive release of antimicrobial ions when the galvanic reactor metal on the implant body is in electrical communication with the antimicrobial ion reservoir.
A bone implant to treat or prevent infection, the implant comprising:
- an implant body having a threaded region configured to be coupled to a bone;
- a removable member comprising a galvanic reactor metal, the removable member configured to be coupled to the implant body within a channel in the implant body;
- an antimicrobial ion reservoir on the implant body;
- wherein the implant is configured to galvanically drive release of antimicrobial ions when the galvanic reactor metal is in electrical communication with the antimicrobial ion reservoir.
Dependencies are inferred from the claim text.