Neural cell extracellular vesicles
AssigneesUniversity of Georgia Research Foundation, Inc., Aruna Bio, Inc.
InventorsSteven L. Stice, Robin Lynn Webb, Tracy A. Stice
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Abstract
Disclosed herein are neural extracellular vesicles (EVs) and methods of using these EVs in the treatment of spinal cord injury, stroke, and traumatic brain injury and neurodegenerative diseases.
Claims30
A method of treating a human subject who has suffered a stroke, comprising administering to the subject an effective amount of a pharmaceutical composition comprising isolated extracellular vesicles (EVs) derived from non-transformed human neural progenitor cells, wherein the EVs are administered intravenously or intranasally.
A method of improving the likelihood of survival of a human subject following a stroke, comprising administering to the subject an effective amount of a pharmaceutical composition comprising isolated extracellular vesicles (EVs) derived from non-transformed human neural progenitor cells, wherein the EVs are administered intravenously or intranasally.
A method of improving sensorimotor function in a human subject following a stroke, comprising administering to the subject an effective amount of a pharmaceutical composition comprising isolated extracellular vesicles (EVs) derived from non-transformed human neural progenitor cells, wherein the EVs are administered intravenously or intranasally.
Dependencies are inferred from the claim text.