Surface structured articles and methods of making the same

A surface structured article comprising a polymer matrix and a dispersed phase, the article having first and second opposed major surfaces, wherein the article comprises a multilayer fluoropolymer film comprising in order:

• a first layer comprising a first polymer, the first polymer comprising at least 35 mole percent tetrafluoroethylene comonomer, at least 15 mole percent vinylidene fluoride comonomer, and at least 5 mole percent hexafluoropropylene comonomer, based on the total mole percent of the first polymer;
• a second layer comprising polyvinylidene fluoride;
• and
• a third layer comprising a third polymer, the third polymer comprising at least 50 mole percent of a methyl methacrylate comonomer, based on the total mole percent of the third polymer, wherein at least a portion of the first major surface is a microstructured, anisotropic surface comprising features having at least one dimension in a range from 1 micrometer to 500 micrometers, wherein the dispersed phase comprises an antimicrobial material, and wherein at least a portion of the dispersed phase is present on the microstructured, anisotropic surface.