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US 11,110,199 B2Granted
Methods for host cell homing and dental pulp regeneration
AssigneeThe Trustees of Columbia University in the City of New York
InventorsHelen H. Lu, Sagaw Prateepchinda, Gunnar Hasselgren
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Abstract
Hydrogel-based scaffolds useful for promoting pulp cell growth and biosynthesis, regulating pulp cell migration and morphology, or both as well as methods for their production and use are provided.
Claims10
A hydrogel-based scaffold for dental pulp formation, said scaffold comprising
- a biosynthetic hydrogel of polymer, fibrinogen, and 1.0-2.0% v/v of PEG-diacrylate,
- wherein fibrinogen is present in the hydrogel-based scaffold at a concentration of 0.5-1.0% w/v for promoting pulp cell growth and biosynthesis, regulating pulp cell migration and morphology, or both.
Dependencies are inferred from the claim text.