US 11,110,145 B2 · Composition for protecting cell from oxidative stress comprising green tea extract which has modified amounts of ingredients

Abstract

Disclosed is to provide a composition which is derived from a natural product and exhibits an excellent effect of protecting cells from oxidative stress and a method for preparing the same. The extract and composition according to one aspect of the present disclosure are derived from a natural product, thus are safe. It can prevent, ameliorate and treat oxidative stress and neuron damage. Therefore, it allows to improve the quality of life of the elderly population without concerns about side effects and promote development of the related industry.

Claims8

Dependent claims

A method for protecting cells from oxidative stress, comprising administering a composition comprising as an active ingredient a green tea extract containing 5 to 25% by weight of (−)-gallocatechin gallate (GCG) and 7 to 15% by weight of (−)-epigallocatechin gallate (EGCG) based on the total weight of the composition to a subject in need thereof,

wherein the total content of the GCG and EGCG in the extract is 40% by weight or less based on the total weight of the composition, and
wherein the GCG and the EGCG are contained in the green tea extract in a weight ratio of 1:1 to 1:2.5.

Dependencies are inferred from the claim text.

Facts

Application

16/110,371Filed 23 Aug 2018

Priority

KR 10-2017-012317425 Sep 2017

Published

US 2019/0091276 A128 Mar 2019

Granted

7 Sep 2021

Term ends

Not estimatedThe source records don’t support an estimate.

Classification6 codes

A61K 36/82
Magnoliopsida: theaceae , e.g. camellia
A61K 31/353
Condensed with carbocyclic rings, e.g. methantheline: 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
A61P 39/06
General protective or antinoxious agents: free radical scavengers or antioxidants
A61K 2236/33
Extraction of the material: involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones

Composition for protecting cell from oxidative stress comprising green tea extract which has modified amounts of ingredients

Life of this patent

Composition for protecting cell from oxidative stress comprising green tea extract which has modified amounts of ingredients

Life of this patent

Abstract

Claims8