Gland or duct diagnostic and treatment methods and related apparatus

A device for treating a gland or duct of a patient comprising:

• a probe having an elongated distal end with an outer diameter of approximately 150 μm or less and a length of approximately 6 mm or less;
• wherein the probe has a longitudinal lumen extending therealong defined by a probe wall and a distal hole through the probe wall in fluid communication with the lumen, the distal hole positioned in the probe distal end;
• wherein the probe lumen comprises a first lumen and a second lumen, and the distal hole comprises a first distal hole in fluid communication with the first lumen and a second distal hole in fluid communication with the second lumen, such that suction can applied to the first lumen while fluid is injected through the second lumen;
• and
• wherein the outer diameter of the elongated distal end is less than that of an adjacent portion of a remainder of the probe to which the elongated distal end is attached.