Tonometry based blood pressure measurements using a two-dimensional force sensor array

A system for determining a blood pressure of a subject human being for ambulatory monitoring, the system comprising:

• a wearable apparatus comprising:
• a pressure sensor array having a plurality of pressure sensors spaced-apart in at least two dimensions, the pressure sensor array generating a plurality of pressure sensor signals, one or more of the pressure sensor signals having data representing amplitudes of one or more arterial pressure waves;
• and
• a wireless transmitter coupled to the pressure sensor array to transmit the plurality of pressure sensor signals;
• a central monitor, comprising:
• a memory circuit;
• a wireless transceiver to receive the transmitted plurality of pressure sensor signals;
• and
• a processor coupled to the wireless transceiver and to the memory circuit, the processor adapted to:
• determine a frequency content of each of the one or more of the pressure sensor signals having data;
• select one or more pressure sensor signals to form a first plurality of selected pressure sensor signals;
• select one or more pressure sensor signals within a selected deviation of a mean of the first plurality of selected pressure sensor signals to form a second plurality of selected pressure sensor signals;
• determine, for each pressure sensor signal in the second plurality of selected pressure sensor signals, a cross-coherence with each nearest neighbor pressure sensor signal;
• identify a pressure sensor signal having a highest mean cross-coherence;
• and
• determine, based on the pressure sensor signal having the highest mean cross-coherence, a systolic blood pressure value and a diastolic blood pressure value.