Methods and compositions for mass spectrometry analysis
OwnerTianxin Wanginventor
Life of this patent
Estimating the term…
Abstract
Methods and compounds are provided to improve the desorption and ionization of analyte for mass spectrometry analysis. More specifically, it is for electrospray ionization (ESI) mass spectrometry. The method uses charged affinity molecules that can bind with analyte either temporarily or permanently to improve the desorption and ionization of analyte. The charged affinity molecules can be positively charged or negatively charged.
Claims5
A compound to improve the signal of non-ionizable analyte molecule that does not contain amine or acid group in electrospray ionization (ESI) mass spectrometry comprising a permanently charged motif and a binding motif selected from cucurbituril and pillararene that can bind with the said analyte molecule to form a non-covalent complex.
Dependencies are inferred from the claim text.