Method for identifying subjects with aggressive melanoma skin cancer at diagnosis
AssigneesUniversiteit Maastricht, Academisch Ziekenhuis Maastricht
InventorsManon Van Engeland, Leander Pieter Jo Van Neste, Karin Van Den Hurk
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Abstract
This disclosure is in the field of molecular biology and medical diagnosis and provides means and methods for determining the prognosis and disease outcome of a subject having a melanoma. More in particular, this disclosure provides a method for determining whether a subject having a melanoma has a poor prognosis, the method comprising the step of determining in a sample from the subject whether the LY75 promoter is methylated and if the LY75 promoter is methylated, classifying the subject as having a poor prognosis.
Claims7
A method for treating a subject having melanoma with adjuvant therapy, the method comprising:
- determining in a sample from the subject that the LY75 promoter is methylated;
- and then treating the subject with adjuvant therapy so as to treat the melanoma.
Dependencies are inferred from the claim text.