Compositions and methods for implantation of processed adipose tissue and processed adipose tissue products
AssigneeThe Johns Hopkins University
InventorsZayna Nahas, Jennifer H. Elisseeff, Iwen Wu
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Abstract
The invention provides compositions and methods for the preparation of processed adipose tissue. The invention further provides methods of use of the processed adipose tissue.
Claims36
An acellular delipidized biocompatible biomaterial comprising a mammalian adipose tissue extracellular matrix (ECM) derived from cadaveric adipose tissue, the biomaterial having between 1% to 0.001% adipose lipid by weight and a complex viscosity of 1×104 to 9×105 Pas, wherein the biomaterial is non-inflammatory when implanted.
An acellular delipidized biocompatible biomaterial comprising a mammalian adipose tissue extracellular matrix (ECM) derived from cadaveric adipose tissue, the biomaterial having between 1% to 0.001% adipose lipid by weight and a complex modulus of 5×103 to 1×105 Pa, wherein the biomaterial is non-inflammatory when implanted.
An acellular delipidized biocompatible biomaterial comprising a mammalian adipose tissue extracellular matrix (ECM) derived from cadaveric adipose tissue, the biomaterial having between 1% to 0.001% adipose lipid by weight and an elastic modulus of 5×103 to 1×105 Pa, wherein the biomaterial is non-inflammatory when implanted.
An acellular delipidized biocompatible biomaterial comprising a mammalian adipose tissue extracellular matrix (ECM) derived from cadaveric adipose tissue, the biomaterial having between 1% to 0.001% adipose lipid by weight and a viscous modulus of 5×103 to 1×105 Pa, wherein the biomaterial is non-inflammatory when implanted.
An acellular delipidized biocompatible biomaterial comprising a mammalian adipose tissue extracellular matrix (ECM) derived from cadaveric adipose tissue, the biomaterial having between 1% to 0.001% adipose lipid by weight and a tan (δ) of 0.05 to 2.0, wherein the biomaterial is non-inflammatory when implanted.
Dependencies are inferred from the claim text.