Catechol-containing adhesive hydrogel, composition for preparing adhesive hydrogel, and compositions each including said adhesive hydrogel
AssigneeJapan Science and Technology Agency
InventorsHiroshi Yabu, Matsuhiko Nishizawa, Kuniaki Nagamine, Yuta Saito, Jun Kamei, Tatsuaki Shimazaki, Shun Chihara
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Abstract
A hydrogel that adheres to the surface of materials is provided by using as constituent elements a water-soluble main chain monomer, crosslinking agent, polymerization initiator, and adhesive monomer having at least a catechol group in a side chain.
Claims22
A composition for preparing adhesive hydrogel including a water-soluble main chain monomer, a crosslinking agent, a polymerization initiator, an adhesive monomer having a catechol group in a side chain, and water, provided that any inorganic nano-silicate in not included.
A method of (i) adhering bone, teeth, or soft tissues, or (ii) of adhering bone, teeth, or soft tissue and a medical member, with an adhesive in a medical field,
- the adhesive comprising a composition for preparing adhesive hydrogel including:
- a water-soluble main chain monomer,
- a crosslinking agent,
- a polymerization initiator,
- an adhesive monomer having a catechol group in a side chain, and
- water,
- wherein the adhesive monomer is added in a proportion of 5% or more to the total number of mol of the main chain monomer and the adhesive monomer,
- and wherein all of the catechol groups of the adhesive monomer can participate in adhesion to a substrate and the hydrogel has a structure in which the catechol groups are present in the polymer in a free state.
Dependencies are inferred from the claim text.