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US 11,078,245 B2Granted
Colon and pancreas cancer peptidomimetics
AssigneePrecision Biologics, Inc.
InventorXue-Ping Wang
Life of this patent
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Abstract
The invention relates to a peptidomimetic of an NPC-1 epitope on the MUC5AC protein which is differentially expressed in pancreatic and colorectal cancer, and diagnostic and therapeutic usages. Further, antibodies that selectively bind the NPC-1 epitope peptidomimetics and may be used in diagnostic and therapeutic methods.
Claims20
An isolated polypeptide comprising a polypeptide having at least 80% identity to the amino acid sequence SLEPEX1DWX2FRYX3NY (SEQ ID NO:
- 3), wherein X1 is E or D;
- X2 is W or Y;
- and X3 is T or I;
- or any one of the amino acid sequences of SEQ ID NOs:
- 6 or 7.
2 more elements
Dependencies are inferred from the claim text.