Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same

A compound selected from a compound represented by following Chemical Formula 5, a pharmaceutically acceptable salt, an optical isomer, a hydrate and a solvate thereof:

• wherein in Chemical Formula 5,
• X1 is N;
• X2 is C(H);
• p is an integer of 1 to 3;
• L6 is a direct bond;
• and
• R17 is represented by Chemical Formulae 3, a1 or a4:
• in Chemical Formula 3,
• Y1 is O;
• Y2 is N;
• Z1, Z2 and Z4 are C(H);
• R21 is hydrogen or C1˜C6 alkyl group;
• Z3 is C(C1˜C6 alkyl;
• wherein in Chemical Formula a1,
• * is a bonding site;
• o is an integer of 0 to 2;
• R23 can be selected from the group consisting of halogen, nitro group, C6˜C14 alkyl group, in case that the R23 is plural, they can be the same as or different from each other;
• wherein in Chemical Formula a4,
• * is a bonding site;
• O is an integer of O or 2;
• R23 is selected from the group consisting of a halogen, a nitro group and C6˜C14 aryl group, in case that the R23 is plural, they can be the same as or different from each other.