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US 11,078,183 B2Granted
Tetrahydrate of H3 ligand, its process of preparation and pharmaceutical compositions comprising the same
AssigneeBioprojet
InventorsMarc Capet, Jeanne-Marie Lecomte, Jean-Charles Schwartz
Life of this patent
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Abstract
The present invention concerns the tetrahydrate form of the compound: (3S)-4-{4-[3-(3-methylpiperidin-1-yl)propoxy]phenyl}pyridine 1-oxide, dihydrochloride, its process of preparation and therapeutical uses thereof.
Claims11
The tetrahydrate form of the compound of formula (A):
- (A):
- (3S)-4-{4-[3-(3-methylpiperidin-1-yl)propoxy]phenyl}pyridine 1-oxide, dihydrochloride.
The tetrahydrate form of the compound of formula (A):
- (A):
- (3S)-4-{4-[3-(3-methylpiperidin-1-yl)propoxy]phenyl}pyridine 1-oxide, dihydrochloride, which exhibits the powder X-ray diffractogram lines:
- 2-Theta° (d in Ångstroms)=9.7 (9.1), 12.5 (7.1), 14.6 (6.1), 15.2 (5.8), 16.5 (5.4), 19.0 (4.7), 19.5 (4.6), 22.0 (4.1), 24.3 (3.7), 24.8 (3.6), 26.2 (3.4), 28.4 (3.1).
Dependencies are inferred from the claim text.