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US 11,077,442 B2Granted
Apparatus and method for extracting pathogens from biological samples
AssigneeTangen Biosciences, Inc.
InventorsJohn Richard Nobile, John F. Davidson
Life of this patent
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Abstract
The disclosed embodiments related to an apparatus and methods for biological sample processing enabling isolation and concentration of microbial or pathogenic constituents from the sample. Sample may be obtained directly from a specimen container, such as a vacutainer, and processed directly without risk of user exposure. The disclosed methods and apparatus provide a convenient and inexpensive solution for rapid sample preparation compatible with downstream analysis techniques.
Claims12
An apparatus to capture pathogens from a biological sample, the apparatus comprising:
- a valve body (120) to fluidically couple a sample tube (130) to each of a syringe body (110, 4A) and a capture tube (135), the valve body (125) having a sample inlet, a first outlet, a second outlet, a channel to connect the sample inlet with each of the first and the second outlets, a first one-way valve (210) to connect the sample inlet with the channel, a second one-way valve (215) to connect the channel to the second outlet and a piercing member (225);
- a syringe body (110) having an outer barrel and an inner barrel, the outer barrel further comprising a first reservoir containing a first reagent;
- and
- a plunger piston configured to moveably couple to the outer syringe barrel, the plunger piston comprising an inner syringe barrel, and outer syringe barrel and a gasket between the first and second reservoirs, the inner syringe barrel defining a second reservoir to receive a second reagent.
1 more element
Dependencies are inferred from the claim text.