Method and system for modulating the brain electrical activity

A method for modulating a composition of a microbiota of an individual comprising the following steps:

• determining a threshold intensity of magnetic pulses by applying to the individual one or more reference magnetic stimulations and determining a reaction of the individual to said one or more reference magnetic stimulations, wherein said reaction corresponds to a right thumb movement;
• and
• repeatedly applying a magnetic stimulation for at least 80 application trains per session of a duration not exceeding 2 seconds each with one time interval between an application train and the next one no less than 20 seconds, wherein said magnetic stimulation has a frequency of at least 18 Hz with an intensity of stimulation of at least 120% of threshold intensity,
• wherein the step of determining a threshold intensity comprises:
• applying the one or more reference magnetic stimulations to a scalp region of the individual corresponding to a primary motor cortex, and
• decreasing an intensity of the one or more reference magnetic stimulations at regular intervals until obtaining the threshold intensity corresponding to a lowest stimulation intensity needed to determine said reaction of the individual.

A system for the deep and repetitive transcranial magnetic stimulation of an individual by means of magnetic pulses applied at least to a scalp region of the individual, said region being at least the a bilateral prefrontal cortex, the system comprising:

• stimulation means for generating and applying a magnetic stimulation, said means comprising a pulse generator of magnetic pulses and stimulating elements;
• and
• computer hardware and software for managing and controlling the magnetic stimulation,
• wherein said computer hardware and software are configured to:
• determine a threshold intensity of the magnetic pulses by applying to the individual one or more reference magnetic stimulations,
• determine a reaction of the individual to said one or more reference magnetic stimulations, wherein said reaction corresponds to a movement of the right thumb, and
• manage the stimulation means so as to perform, after the determination of the threshold intensity, the magnetic stimulation comprising at least 80 application trains per session of a duration not exceeding 2 seconds each with a time interval between an application train and the next one not less than 20 seconds, said magnetic stimulation having a pulse frequency of at least 18 Hz and a stimulation intensity of at least 120% of the threshold intensity,
• wherein the step of determining a threshold intensity comprises:
• applying the one or more reference magnetic stimulations to a scalp region of the individual corresponding to a primary motor cortex, and
• decreasing an intensity of the one or more reference magnetic stimulation at regular intervals until obtaining the threshold intensity corresponding to a lowest stimulation intensity needed to determine said reaction of the individual.