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US 11,077,204 B2Granted
Compositions comprising antibody-duocarmycin drug conjugates
AssigneeByondis B.V.
InventorsNiels Jaap Osinga, Ernst Johannes Bernardus Van Bockxmeer
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Abstract
The present invention relates to lyophilized compositions comprising antibody-duocarmycin drug conjugates.
Claims25
A lyophilized composition comprising an antibody-drug conjugate of formula (I),
- a buffering agent, a lyoprotectant, and a surfactant wherein the molar ratio of lyoprotectant to antibody-drug conjugate is 1,400-3,200 to 1, wherein mAb is a monoclonal antibody.
A composition comprising an antibody-drug conjugate of formula (I),
- a buffering agent, a lyoprotectant, a surfactant, and water, wherein the molar ratio of lyoprotectant to antibody-drug conjugate is 1,400-3,200 to 1, wherein mAb is a monoclonal antibody.
Dependencies are inferred from the claim text.