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US 11,077,094 B2Granted
Spiro-lactam NMDA receptor modulators and uses thereof
AssigneeAptinyx Inc.
InventorsJohn A. Lowe, III, M. Amin Khan
Life of this patent
Estimating the term…
Abstract
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related disorders. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
Claims2
A compound represented by:
- or a pharmaceutically acceptable salt thereof.
A pharmaceutical composition, the pharmaceutical composition comprising:
- a compound represented by:
- or a pharmaceutically acceptable salt thereof;
- and
- a pharmaceutically acceptable excipient.
1 more element
Dependencies are inferred from the claim text.