Non-vented vial access syringe

A vial access system comprising:

• a syringe comprising:
• a barrel tube and a plunger tube;
• the barrel tube comprising a proximal end portion, a distal end portion, a first liquid passage;
• and a first gas passage, wherein a first fluid volume is formed between the barrel tube and the plunger tube, and the plunger tube comprises a second fluid volume, and wherein the first liquid passage extends through the proximal end portion of the barrel tube to the first fluid volume, and the first gas passage extends through the proximal end portion of the barrel tube to the second fluid volume;
• and
• a vial adapter comprising:
• a proximal end portion having a needle configured to couple with a vial;
• a cavity extending into the vial adapter and configured to receive a portion of the syringe therein, the cavity comprising a recess extending around an inner surface of the cavity;
• a second gas passage extending between the recess of the cavity and the needle;
• and a second liquid passage extending between the recess of the cavity and the needle,
• wherein, when the syringe is coupled to the vial adapter, the second gas passage is fluidly coupled with the first gas passage of the syringe, and the second liquid passage is fluidly coupled with the first liquid passage of the syringe.