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US 11,029,287 B2Granted
Multi-focus optical-resolution photoacoustic microscopy with ultrasonic array detection
AssigneeCalifornia Institute of Technology
InventorsLihong Wang, Liang Song, Konstantin Maslov, Bin Rao
Life of this patent
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Abstract
A probe for use with an imaging system, including a scanning device configured to receive a first light beam from a light source, a beam-divider configured to split the first light beam into a plurality of second light beams, and a focusing device configured to focus each of the second light beams on respective locations in an object of interest is disclosed.
Claims18
An imaging method, comprising:
- receiving a first light beam from a light source;
- splitting the first light beam into a plurality of second light beams using a beam-divider;
- focusing the plurality of second light beams on respective locations in an object of interest using a focusing device, the plurality of second light beams causing the object of interest to emit acoustic signals, wherein the plurality of second light beams and the acoustic signals are coaxially aligned on opposite sides of the object of interest in a transmission mode;
- and
- receiving the acoustic signals from the object of interest using an ultrasonic transducer array.
2 more elements
An imaging method, comprising:
- receiving a first light beam from a light source;
- splitting the first light beam into a plurality of second light beams using a beam-divider;
- focusing the plurality of second light beams on respective locations in an object of interest using a focusing device, the plurality of second light beams causing the object of interest to emit acoustic signals;
- coaxially merging the plurality of second light beams and the acoustic signals using an optical-acoustic beam combiner;
- and
- receiving the acoustic signals from the object of interest using an ultrasonic transducer array.
3 more elements
An imaging method, comprising:
- receiving a first light beam from a light source;
- splitting the first light beam into a plurality of second light beams using a beam-divider, wherein the beam-divider comprises a transmission grating;
- focusing the plurality of second light beams on respective locations in an object of interest using a focusing device, the plurality of second light beams causing the object of interest to emit acoustic signals;
- and
- receiving the acoustic signals from the object of interest using an ultrasonic transducer array.
2 more elements
An imaging method, comprising:
- receiving a first light beam from a light source;
- splitting the first light beam into a plurality of second light beams using a beam-divider;
- focusing the plurality of second light beams on respective locations in an object of interest using a focusing device, the plurality of second light beams causing the object of interest to emit acoustic signals;
- and
- receiving the acoustic signals from the object of interest using an ultrasonic transducer array,
- wherein receiving the acoustic signals from the object of interest using the ultrasonic transducer array comprises simultaneously receiving a plurality of acoustic signals, each acoustic signal in the plurality of acoustic signals being emitted substantially simultaneously but from a different one of the respective locations in the object of interest.
3 more elements
An imaging system, comprising:
- a scanning device configured to steer a first light beam from a light source through a beam-divider, wherein the scanning device comprises at least one of a mechanically scanning mirror, a galvanometer, a polygon scanner, an acoustic-optical scanner, and an electro-optical scanner;
- the beam-divider configured split the first light beam into a plurality of second light beams;
- a focusing device configured to focus the plurality of second light beams onto respective locations in an object of interest being imaged, the plurality of second light beams causing the object of interest to emit acoustic signals;
- and
- one or more ultrasonic detection devices configured to receive the acoustic signals from the object of interest.
2 more elements
Dependencies are inferred from the claim text.