Sample detection device
AssigneeUniversity Court of the University of St Andrews
InventorsRobert J. H. Hammond, Stephen H. Gillespie
Life of this patent
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Abstract
An apparatus (150) comprises a first detection chamber (130) for receiving microorganisms and configured to allow detection of the microorganisms via detection of scattered light from the first detection chamber (130); a medium (120) configured to permit passage of microorganisms from a sample (110) through the medium (120) into the first detection chamber (130); and at least one second detection chamber (140) configured to allow detection of the microorganisms via detection of scattered light from the at least one second detection chamber (140).
Claims33
An apparatus comprising a one-piece cartridge, the cartridge comprising:
- a specimen chamber for receiving a sample;
- a first detection chamber for receiving microorganisms and configured to allow detection of the microorganisms via detection of scattered light from the first detection chamber;
- a medium comprising a semipermeable membrane configured to permit passage of the microorganisms from the sample through the medium into the first detection chamber;
- wherein the specimen chamber and the first detection chamber form separate chambers, the one-piece cartridge having walls defining the specimen chamber and the first detection chamber, respectively;
- and
- at least one second detection chamber configured to allow detection of the microorganisms via detection of scattered light from the at least one second detection chamber, wherein the at least one second detection chamber contains a substance potentially capable of inhibiting growth of the microorganisms, the substance comprising an antibiotic in freeze-dried form.
A one-piece cartridge comprising:
- a specimen chamber for receiving a sample;
- a first detection chamber for receiving microorganisms and configured to allow detection of the microorganisms via detection of scattered light from the first detection chamber;
- a medium comprising a semipermeable membrane configured to permit passage of the microorganisms from the sample through the medium into the first detection chamber;
- wherein the specimen chamber and the first detection chamber form separate chambers, the one-piece cartridge having walls defining the specimen chamber and the first detection chamber, respectively;
- and
- at least one second detection chamber configured to allow detection of the microorganisms via detection of scattered light from the second detection chamber, wherein the at least one second detection chamber contains a substance potentially capable of inhibiting growth of the microorganisms, the substance comprising an antibiotic in freeze-dried form.
A method for monitoring a biological material, the method comprising:
- introducing a biological sample into a specimen chamber;
- allowing selective passage of microorganisms from the biological sample in the specimen chamber through a medium comprising a semipermeable membrane into a first detection chamber;
- emitting light into the first detection chamber so that the light at least partly passes through and is scattered by the biological sample, and detecting light scattered in the first detection chamber;
- and
- emitting light into at least one second detection chamber so that the light at least partly passes through and is scattered by the biological sample, and detecting light scattered in the at least one second detection chamber, wherein the at least one second detection chamber contains a substance potentially capable of inhibiting growth of the microorganisms, the substance comprising an antibiotic in freeze-dried form.
Dependencies are inferred from the claim text.