Detergent composition comprising protease and amylase variants

A detergent composition comprising:

• (i) at least one alpha amylase variant comprising modifications to amino acid positions corresponding to amino acid positions selected from the group consisting of:
• H1*+N54S+V56T+G109A+Q169E+Q172K+A174*+G182*+D183*+N195F+V206L+K391A+G476K;
• H1*+N54S+V56T+G109A+R116H+A174S+G182*+D183*+N195F+V206L+K391A+G476K;
• H1*+N54S+V56T+K72R+G109A+F113Q+R116Q+W167F+Q172G+A174S+G182*+D183*+G 18 4T+N195F+V206L+K391A+P473R+G476K;
• H1*+N54S+V56T+G109A+F113Q+R116Q+Q172N+A174S+G182*+D183*+N195F+V206L+A26 5G+K391A+P473R+G476K;
• H1*+N54S+V56T+K72 R+G 109A+F113Q+W167F+Q172R+A174S+G182*+D183*+N195F+V206L+K391A+G476K;
• H1*+N54S+V56T+K72R+G109A+R116H+T134E+W167F+Q172G+L173V+A174S+G182*+D183*+N195F+V206L+G255A+K391A+G476K;
• H1*+N54S+V56T+K72R+G109A+R116H+T134E+W167F+Q172G+L173V+A174S+G18 2*+D183*+N195F+V206L+G255A+K391A+Q395P+T444Q+P473R+G476K;
• H1*+N54S+V56T+G109A+T134E+A174S+G182*+D183*+N195F+V206L+K391A+G476 K;
• H1*+N54S+V56T+K72R+G109A+A174S+G182*+D183*+N195F+V206L+G255A+K391A+G476K;
• and
• H1*+N54S+V56T+G109A+W167F+Q172E+L173P+A174K+G182*+D183*+N195F+V206L+K391A+G476K of the amino acid sequence of SEQ ID NO:
• 1,
• wherein said alpha-amylase variant shares at least 85%, but less than 100% sequence identity with the amino acid sequence of SEQ ID NO:
• 1, and wherein said alpha-amylase variant has alpha-amylase activity;
• and
• (ii) at least one protease having protease activity, wherein said protease is selected from the group consisting of:
• (a) a protease having at least 85% sequence identity to the amino acid sequences of SEQ ID NOs:
• 2, 3, 19, 20, or 23;
• (b) a protease variant comprising a substitution at one or more amino acid positions corresponding to amino acid positions 171, 173, 175, 179, or 180 of the amino acid sequence of SEQ ID NO:
• 2, wherein said protease variant has at least 85% but less than 100% sequence identity to the amino acid sequence of SEQ ID NO:
• 2;
• (c) a protease variant comprising a modification in one or more amino acid positions corresponding to amino acid positions 32, 33, 48, 49, 50, 51, 52, 53, 54, 58, 59, 60, 61, 62, 94, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 116, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 150, 152, 153, 154, 155, 156, 158, 159, 160, 161, 164, 169, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 185, 186, 197, 198, 203, 204, 205, 206, 207, 208, 209, 210, 211, 212, 213, 214, 215, or 216 of the amino acid sequence of SEQ ID NO:
• 3,
• (d) a protease variant comprising a substitution in one or more amino acid positions corresponding to amino acid positions 9, 15, 27, 42, 52, 55, 56, 59, 60, 66, 74, 85, 97, 99, 101, 102, 104, 116, 118, 154, 156, 157, 158, 161, 164, 176, 179, 182, 185, 188, 198, 199, 200, 203, 206, 210, 211, 212, 216, 230, 232, 239, 242, 250, 253, 255, 256, or 269, of the amino acid sequence of SEQ ID NO:
• 3, wherein said protease variant has at least 85% sequence identity to the amino acid sequence of SEQ ID NO:
• 3, and
• (e) a protease variant comprising a substitution in one or more amino acid positions corresponding to amino acid positions 32, 33, 49, 50, 51, 52, 53, 54, 55, 60, 61, 62, 63, 64, 96, 97, 98, 99, 100, 101, 102, 103, 104, 105, 106, 107, 108, 109, 118, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 152, 154, 155, 156, 157, 158, 161, 162, 163, 167, 170, 175, 181, 187, 183, 184, 185, 186, 187, 188, 189, 190, 191, 192, 203, 204, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221, or 222 of the amino acid sequence of SEQ ID NO:
• 23,
• wherein said protease variant has at least 85% sequence identity to the amino acid sequence of SEQ ID NO:
• 23.