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US 11,028,140 B2Granted
Osteogenic biomaterial
AssigneeNortheast Ohio Medical University
InventorFayez Safadi
Life of this patent
Estimating the term…
Abstract
A composition for enhancing bone tissue repair or regeneration is described. The composition includes osteoactivin or an active peptide fragment thereof and a biocompatible material. Osteogenic orthopedic devices including the osteoactivin-containing composition are also described. The devices and compositions can be used in methods for enhancing bone tissue repair or regeneration by contacting a site in need of bone repair or regeneration in a subject with the osteoactivin-containing composition.
Claims13
A composition for enhancing bone tissue repair or regeneration, comprising:
- an active peptide fragment of osteoactivin having the amino acid sequence of SEQ ID NO:
- 1, and
- a biocompatible polymer;
- wherein the biocompatible polymer is covalently bound to the active peptide fragment of osteoactivin.
1 more element
Dependencies are inferred from the claim text.