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US 11,028,138 B2Granted
Compositions and methods for using actin-based peptides to modulate cellular bioactivity and cellular susceptibility to intracellular pathogens
OwnerYuntao Wuinventor
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Abstract
Compositions and methods for using actin-based peptides to modulate cellular bioactivity, including modulation of cellular susceptibility to intracellular pathogens, such as bacteria and viruses.
Claims15
An actin-based peptide, comprising
- an actin core domain and a cell penetration domain, operably linked together by a spacer domain,
- wherein an N-terminus or C-terminus may have either the actin core domain or the cell penetration domain;
- and
- wherein the actin core domain is a B11 core domain having the sequence of YVALDFE, which are the amino acid residues 3-9 of SEQ ID NO:857.
1 more element
Dependencies are inferred from the claim text.