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US 11,027,272 B1Granted
Transfer dispensers for assay devices
AssigneePlexium, Inc.
InventorsKandaswamy Vijayan, Kapil Mahakalkar, Yi Zhang
Life of this patent
Estimating the term…
Abstract
Disclosed are transfer dispensers for assay devices. These dispensers provide for transfer of a single assay component into a single well in the assay device. This ensures that the assay conducted in each well contains only a single component.
Claims29
A device comprising:
- a) a transfer dispenser having a multiplicity of cavities wherein each cavity has an opening diameter and is configured to reversibly hold only a single bead, and
- b) an assay device which comprises a multiplicity of wells, wherein the assay device and the transfer dispenser are configured to fit onto or mate with each other, with a gap being present between said assay device and said transfer device, and wherein the cavities of the transfer dispenser are aligned with the wells of the device when the assay device and the transfer dispenser are fitted onto or mated with each other;
- wherein each well has an opening diameter that is larger than the opening diameter of each of said cavities such that, when each cavity is placed over each well, a containment space is formed comprising said cavity and said well;
- wherein the single bead is released from the cavity through said containment space and deposited into said well;
- wherein the beads are non-magnetic beads,
- wherein said gap has a size that is smaller than a size of the bead being transferred within the device, and
- wherein the transfer dispenser is configured to be inverted relative to the assay device.
4 more elements
A device comprising:
- a) a transfer dispenser having a multiplicity of cavities wherein each cavity has a opening diameter and is configured to reversibly hold only a single bead, and
- b) an assay device which comprises a multiplicity of wells, wherein the assay device and the transfer dispenser are configured to fit onto or mate with each other, optionally with a gap being present between said assay device and said transfer device, and wherein the cavities of the transfer dispenser are aligned with the wells of the device when the assay device and the transfer dispenser are fitted onto or mated with each other;
- wherein each well has an opening diameter that is larger than the opening diameter of each of said cavities such that, when each cavity is placed over each well, a containment space is formed comprising said cavity and said well;
- wherein the single bead is released from the cavity through said containment space and deposited into said well;
- wherein the beads are non-magnetic beads;
- wherein said gap when present has a size that is smaller than a size of the bead being transferred within the device, and
- wherein the transfer dispenser is configured to be inverted relative to the assay device.
4 more elements
A device comprising:
- a) a transfer dispenser having a multiplicity of cavities wherein each cavity has an opening diameter and is configured to reversibly hold only a single bead, and
- b) an assay device which comprises a multiplicity of wells, wherein the assay device and the transfer dispenser are configured to fit onto or mate with each other, and wherein the cavities of the transfer dispenser are aligned with the wells of the device when the assay device and the transfer dispenser are fitted onto or mated with each other;
- wherein each well has an opening diameter that is larger than the opening diameter of each of said cavities such that, when each cavity is placed over each well, a containment space is formed comprising said cavity and said well;
- wherein the single bead is released from the cavity through said containment space and deposited into said well;
- wherein the beads are non-magnetic beads;
- wherein the transfer dispenser and the assay device are in direct contact with each other, and
- wherein the transfer dispenser is configured to be inverted relative to the assay device.
4 more elements
Dependencies are inferred from the claim text.