Radiation therapy system with multiple X-ray imagers for near real-time localization

A radiation treatment system comprising:

• a gantry that is rotatably coupled to a drive stand and is configured to rotate about a bore of the radiation treatment system;
• a treatment-delivering X-ray source mounted on the gantry and configured to direct treatment X-rays to a target volume disposed in the bore;
• a first imaging X-ray source mounted on the gantry and configured to direct first X-rays through the target volume and toward a first X-ray imager mounted on the gantry;
• a second imaging X-ray source mounted on the gantry and configured to direct second X-rays through the target volume and toward a second X-ray imager mounted on the gantry;
• and
• a processor configured to:
• cause the gantry to perform a rotation continuously in a first direction, wherein the rotation includes an imaging arc and a treatment arc that follows the imaging arc and starts at a first treatment delivery position;
• while causing the gantry to rotate through the imaging arc from a first imaging position to the first treatment delivery position, receive first volumetric image data from the first X-ray imager and second volumetric image data from the second X-ray imager;
• determine a first current location of the target volume based on the first volumetric image data and the second volumetric image data;
• and
• in response to a determination that the first current location of the target volume is less than a threshold distance from a planned treatment location, while causing the gantry to rotate through the treatment arc:
• initiate delivery of a treatment beam of the treatment-delivering X-ray source to the target volume;
• and
• continue to cause the gantry to rotate in the first direction from the first treatment delivery position to a second treatment delivery position.