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US 11,027,115 B2Granted
Systems and methods for electroporation
AssigneeMayo Foundation for Medical Education and Research
InventorsSamuel J. Asirvatham, Paul A. Friedman
Life of this patent
Estimating the term…
Abstract
This document describes methods and materials for improving treatment of hypertension. For example, this document describes methods and devices for electroporation of nerves in the renal area to treat hypertension.
Claims20
A system for providing electroporation, the system comprising:
- a first electrode and a second electrode configured to be placed in a renal area of a patient;
- a sensor;
- and
- a pulse generator coupled to the first electrode, the second electrode, and the sensor, the pulse generator comprising:
- a memory that is capable of storing computer executable instructions;
- and
- a processor that is configured to facilitate execution of the executable instructions stored in the memory, wherein the instructions cause the processor to:
- generate, via the pulse generator, a stimulation electrical current to cause stimulation between the first electrode and the second electrode for the renal area;
- detect, via the sensor, a change in blood pressure of the patient resulting from the stimulation electrical current;
- and
- in response to detecting the change in blood pressure of the patient, generate an electroporation electrical current to cause reversible or irreversible electroporation between the first electrode and the second electrode for the renal area.
8 more elements
A method of providing electroporation, the method comprising:
- placing a first electrode and a second electrode in a renal area of a patient;
- generating, via a pulse generator, a stimulation electrical current to cause stimulation between the first electrode and the second electrode for the renal area;
- detecting, via a sensor, a change in blood pressure of the patient resulting from the stimulation electrical current;
- and
- in response to detecting the change in blood pressure of the patient, generating an electroporation electrical current to cause reversible or irreversible electroporation between the first electrode and the second electrode for the renal area.
2 more elements
Dependencies are inferred from the claim text.