Emergency devices
AssigneeAdamis Pharmaceuticals Corporation
InventorsMark J. Flather, Karen K. Daniels, Thomas Moll, Ronald B. Moss, Dennis J. Carlo
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Abstract
Described herein are syringe devices comprising a syringe including a therapeutic dose of at least one drug to be used in a drug or substance overdose. Also provided herein are compositions and methods of treating opioid overdose using high dose naloxone.
Claims18
A high dose naloxone composition including naloxone at a dose greater than or equal to about 5 mg configured for administration, wherein Cmax is between 15 ng/mL to 24 ng/mL and the administration is an injection.
A high dose naloxone composition including naloxone at a dose greater than about 5 mg configured for administration, wherein the AUC0-0.04 h is between 0.01 h*ng/mL and 0.1 h*ng/mL and the administration is an injection.
A high dose naloxone composition including naloxone at a dose greater than or equal to about 5 mg configured for administration, wherein the AUC0-0.08 h is between 0.05 h*ng/mL to 0.2 h*ng/mL and the administration is an injection.
Dependencies are inferred from the claim text.