US 11,027,070 B2Granted

Medical device for fluid delivery having reduced dead space

AssigneeWest Pharma. Services IL, Ltd.

InventorOz Cabiri

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Abstract

Disclosed herein is a pharmaceutical syringe having a cylindrical bore with a proximal opening, the syringe comprising a distal wall of the bore defining an outlet biased from the central axis of the syringe, and toward a first area of the distal wall and biased from the central axis away from a second area distinct from the first area; the syringe comprising a plunger seal having a distal surface; wherein when the plunger seal is fitted into the bore with the distal surface facing an inner surface of the distal wall of the bore, the second area of the inner surface is axially closer to the distal surface of the plunger seal than the first area, in a direction parallel to the central axis of the cylindrical bore, such that fluid is expelled from the second area and towards the outlet.

Claims20

Dependent claims

A pharmaceutical syringe comprising:

a cylindrical bore having a proximal opening, a distal wall having an inner surface, an interior surface extending from said proximal opening to said distal wall, and a central axis, said inner surface having a first area and a second area distinct from said first area, said distal wall of said cylindrical bore defining an outlet, said outlet being spaced from said central axis toward said first area and away from said second area;
a hub extending from said distal wall, said hub defining a hub outlet and a fluid path extending from said outlet of said cylindrical bore to said hub outlet;
and
a plunger seal positioned within and coaxial to said cylindrical bore, said plunger seal having a side surface configured to slidingly engage the interior surface of the cylindrical bore, a distal surface defining a center, the distal surface extending either perpendicular to said central axis or proximally as it extends radially from said center to said side surface;
wherein when said plunger seal is fitted within said cylindrical bore with said distal surface facing said inner surface of said distal wall of said cylindrical bore, said second area of said inner surface is axially closer to said distal surface of said plunger seal than said first area, in a direction parallel to said central axis of said cylindrical bore, allowing said second area to contact said distal surface of said plunger seal before said distal surface contacts said first area.

2 more elements

A method for reducing fluid dead space in a pharmaceutical syringe comprising a cylindrical bore with a proximal opening and a distal end including a fluid outlet spaced from a central axis of the cylindrical bore and an interior surface extending from said proximal opening to said distal end, and a hub extending from said distal end of said cylindrical bore, said hub defining a hub outlet and a fluid path extending from said outlet of said cylindrical bore to said hub outlet, and said cylindrical bore fitting a plunger seal having a distal surface, the plunger seal having a side surface configured to slidingly engage the interior surface of the cylindrical bore, the method comprising:

driving said plunger seal towards said distal end of said cylindrical bore, the distal surface of said plunger seal extending either perpendicular to said central axis or proximally as it extends radially from said central axis to said side surface;
contacting a portion of said distal surface of said plunger seal with a portion of an inner surface of a wall of said distal end of said cylindrical bore at a contact area distinct from an area comprising the fluid outlet;
and
expanding a range of contact from said contact area towards the location of the fluid outlet while expelling fluid in a mean direction which is tilted with respect to a mean direction of said distal surface of said plunger seal,
wherein said contacting at said contact area comprises contacting said distal surface of said plunger seal before contacting said area comprising the fluid outlet.

2 more elements

Dependencies are inferred from the claim text.

Facts

Application: 15/766,598Filed 10 Oct 2016 · continuation
Priority: 22 Sep 2015
Published: US 2018/0296763 A118 Oct 2018
Granted: 8 Jun 2021
Term ends: Not estimatedThe source records don’t support an estimate.

Classification23 codes

A61M 5/28
Syringes: syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
A61M 5/3134
Syringe barrels: characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
A61M 5/3202
Needles; Details of needles pertaining to their connection with syringe or hub ; Accessories for bringing the needle into, or holding the needle…:…
A61M 5/3204
Devices for protection of the needle before use, e.g. caps: needle cap removers, i.e. devices to dislodge protection cover from needle or needle…

Family

Application14/861,478Parent of this continuation-in-part · filed 22 Sep 2015
Application62/284,806Us provisional application · filed 9 Oct 2015
Application62/281,536Us provisional application · filed 21 Jan 2016
Application15/204,542Parent of this continuation · filed 7 Jul 2016
Application15/269,248Parent of this continuation · filed 19 Sep 2016
US 2018/0296763 A1Pre-grant publication · published 18 Oct 2018
US 10,576,207 B2Parent of this continuation
US 10,086,145 B2Parent of this continuation
US 9,987,432 B2Parent of this continuation-in-part
Application15/269,248Parent of this continuation-in-part
US 2017/0080157 A1Published application
US 2017/0080158 A1Published application
US 2017/0100542 A1Published application
US 11,027,070 B2This patent

From the US filing history. Foreign family members aren’t listed.

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