Natural type miRNA for controlling gene expression, and use of same
AssigneeBonac Corporation
InventorsEriko Aoki, Yasuhiko Yoshida, Shiori Kato, Tadaaki Ohgi
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AssigneeBonac Corporation
InventorsEriko Aoki, Yasuhiko Yoshida, Shiori Kato, Tadaaki Ohgi
Estimating the term…
The present invention provides a natural type miRNA, which is a single-stranded nucleic acid containing X region and Y region, wherein the 3′-terminus of said X region and the 5′-terminus of said Y region are linked via a linker region of a non-nucleotide structure, the X region contains (a) a guide strand sequence or (b) a passenger strand sequence of a mature miRNA, when the X region contains (a), the Y region contains a passenger strand sequence of the mature miRNA, when the X region contains (b), the Y region contains a guide strand sequence of the mature miRNA, and the guide strand sequence and the passenger strand sequence form a double-stranded structure.
A single-stranded nucleic acid comprising X region and Y region,
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