Compositions and methods of use thereof to promote muscle growth and function
AssigneeIngenious Ingredients, LP
InventorsMartin Purpura, Ralf Jaeger, Shawn Wells, Kylin Lao, Anton Fliri
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Abstract
The disclosed compositions and methods relate to the increasing muscle mass, preventing muscle atrophy, promoting muscle growth, as well as treatment of various other conditions and diseases. In certain aspects, the disclosed compositions are comprised dileucine and leucine and pharmaceutically acceptable salts thereof. In certain aspects, disclosed compositions are administered to subjects in need thereof to increase muscle mass, prevent muscle atrophy, and/or promote muscle growth.
Claims20
A composition for increasing muscle protein synthesis comprising:
- a. dileucine, and
- b. leucine
- wherein the dileucine is present in an amount of at least about 50% (w/w) of the combined weight of dileucine and leucine.
A method for treating muscle atrophy in a subject or preventing muscle atrophy in a subject at risk for muscle atrophy, the method comprising administering to the subject an effective amount of a composition comprising leucine and dileucine wherein the dileucine is present in an amount of at least about 50% (w/w) of the combined weight of dileucine and leucine.
A method for increasing muscle protein synthesis in a subject, the method comprising administering to the subject an effective amount of a composition comprising leucine and di-leucine, wherein the dileucine is present in an amount of at least about 50% (w/w) of the combined weight of dileucine and leucine and wherein administration of the composition of to the subject increases muscle protein synthesis in the subject.
Dependencies are inferred from the claim text.