PUM 1 protein as target for virus inhibition
AssigneeShenzhen International Institute for Biomedical Research
InventorsGrace Zhou, Bernard Roizman, Yonghong Liu
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Abstract
Disclosed is a method for prophylaxis or treatment of infection of a virus, or for modulating innate immunity, in a subject comprising administering to the subject a therapeutically effective amount of a PUM1 inhibitor. A pharmaceutical composition comprising the PUM1 inhibitor is also disclosed.
Claims13
A method for treatment of infection of a virus in a subject, comprising administering to the subject a therapeutically effective amount of a PUM1 inhibitor, wherein the PUM1 inhibitor is an antisense oligomer that targets a nucleic acid molecule encoding PUM1 to block the synthesis of PUM1 wherein the virus is Hepres Simplex Virus type 1 or type 2.
Dependencies are inferred from the claim text.