Therapeutical composition containing apomorphine as active ingredient

A method of administering a pharmaceutical composition to a patient in need thereof, the composition having an active substance and being provided in the form of a solution, the pharmaceutical composition comprising:

• i) apomorphine as the active substance;
• ii) a water miscible co-solvent;
• iii) an antioxidant;
• iv) water;
• v) optionally, a surfactant;
• and
• vi) optionally, a pH modifier;
• wherein a pH of the composition is greater than 4, and
• wherein the pharmaceutical is administered through a needle with a 27 Gauge or larger.

A pharmaceutical composition for parenteral administration by injection having an active substance and being provided in the form of a solution, the pharmaceutical composition comprising:

• i) apomorphine as the active substance;
• ii) a water miscible co-solvent;
• iii) an antioxidant;
• iv) water;
• v) optionally, a surfactant;
• and
• vi) optionally, a pH modifier;
• wherein a pH of the pharmaceutical composition is greater than 4,
• wherein the pharmaceutical composition is administrable through a needle with a 27 Gauge or larger, and
• wherein an amount of the active substance is between about 10 to 70 mg/ml.