US 11,026,935 B2Granted

Free base crystalline form of a complement component C5a receptor

AssigneeChemoCentryx, Inc.

InventorsRajinder Singh, Kwok Yau, Yibin Zeng, Penglie Zhang, Rebecca M. Lui, Antoni Krasinski

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Abstract

Provided herein is a free base crystalline form of a complement component 5a receptor having the formula of Compound 1 Also provided herein are pharmaceutical compositions and methods of treatment using the crystalline free base form of Compound 1 described herein.

Claims9

Dependent claims

A free base crystalline form of Compound 1

characterized by an X-ray powder diffraction (XRPD) pattern comprising peaks at 8.1, 8.4, 14.1, 16.9, and 19.0 degrees 2θ (±0.2 degrees 2θ).

Dependencies are inferred from the claim text.

Facts

Application: 17/091,019Filed 6 Nov 2020 · us provisional application
Priority: 8 Nov 2019
Published: US 2021/0137907 A113 May 2021
Granted: 8 Jun 2021
Term ends: Not estimatedThe source records don’t support an estimate.

Classification13 codes

A61K 31/451
Non condensed piperidines, e.g. piperocaine: having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine,…
A61K 31/675
Phosphorus compounds: having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
A61K 39/3955
Against materials from animals: against proteinaceous materials, e.g. enzymes, hormones, lymphokines
A61P 3/10
For glucose homeostasis: for hyperglycaemia, e.g. antidiabetics

Family

Application62/932,652Us provisional application · filed 8 Nov 2019
US 2021/0137907 A1Pre-grant publication · published 13 May 2021
US 11,026,935 B2This patent

From the US filing history. Foreign family members aren’t listed.

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