Polymeric drug delivery systems for treatment of disease
AssigneeBoard of Regents, The University of Texas System
InventorsChun Li, Jun Zhao, Jason Fleming
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Abstract
Provided are compositions and nanoparticle formulations that may be used, e.g., to deliver a therapeutic compound to a subject. In some embodiments, the nanoparticles may be used to deliver one or more chemotherapeutic agents to treat a cancer such, e.g., as a pancreatic ductal adenocarcinoma.
Claims22
A polymer, wherein the polymer is a block copolymer comprising a polyacrylic acid backbone with a first plurality of PEG sidechains and a second plurality of ε-caprolactone sidechains, and wherein the ε-caprolactone sidechains terminates with carboxy, phosphonate, or hydroxysulfonyl.
Dependencies are inferred from the claim text.