Devices and methods for excluding the left atrial appendage

A self-expandable, atraumatic occlusion device configured to conform to the side wall of a left atrial appendage, comprising:

• a compressible open cell foam body, having a tubular foam side wall and a central cavity;
• a self-expandable support within the cavity;
• anchors having tips configured to extend radially outwardly and incline proximally through the side wall to penetrate tissue of the left atrial appendage;
• and
• a proximal end wall forming a closed proximal end on the foam body;
• wherein the proximal end wall is positioned proximally of a proximal end of the support, and the foam side wall extends distally beyond the distal end of the support to form a distal, atraumatic bumper for preventing contact between the support and a wall of the left atrial appendage in an implantation in which a central longitudinal axis of the occlusion device is non-parallel to a primary longitudinal axis of the left atrial appendage.

A left atrial appendage occlusion device, comprising:

• an expandable tubular foam cup having a closed proximal end, a distal end, a tubular side wall and a proximal end wall, the side wall having a thickness of at least about 1.0 mm and a porosity of at least about 85% open void content;
• an expandable frame configured to press the side wall into conforming contact with a wall of the left atrial appendage;
• and
• anchors having tips configured to extend radially outwardly and incline proximally through the side wall to penetrate tissue of the left atrial appendage.